Wednesday, January 23, 2013

Diabetes Weight-Loss Study Ends Early With Surprising Result ...

Old Yesterday, 01:07 PM ? #1

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Saw this when it came out. And interestingly, it accords with the experience of a client I worked with a little over a year ago. She was a very heavy, Type II diabetic who had survived a heart attack. Her doctor read her the riot act and basically ordered her to lose weight.

I received a letter from her doctor directing me to supervise a 1,200 calorie diet and to encourage increased activity. So, I helped my client to configure an eating plan that would have her operating within her calorie allowance and had her on a walking program. I also worked with a registered dietician whose chief recommendation was to have my client eating a half-cup of yogurt before bedtime.

Results: client lost in excess of 10% of her bodyweight in short order. Over a period of 6-8 weeks her daily blood sugar ratings dropped from 400-500 (kid you not) to between 80-120. Her A1C dropped from above 13 to below 10 during that time.

She and I discontinued our working relationship shortly thereafter, but I continued to check on her periodically, at which times she'd enthusiastically report that she was maintaining her weight-loss, within a few pounds, and was walking several miles a day.

Her doctor and dietician were ecstatic. And by every measure, my client was a stunning success story ... until she had another heart attack.

She's fine now. Oh, the study:

http://www.nih.gov/news/health/oct2012/niddk-19.htm

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Old Yesterday, 02:45 PM ? #2

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Glad she is fine.

A couple of thoughts....

Does she have a family history of cardiovascular disease? That is also a semi-rhetorical question. Just because she can answer that question as a "NO" to the best of her knowledge doesn't me that the absolute answer is NO. The history could have been there without people realizing it. If the answer is "yes"... genetics are funny like that, and they can't be beat.

Had she always maintained a "healthy weight" and not gotten very heavy, with Type 2 Diabetes in the first place.. would she have had the first heart attack to begin with? (i.e. did she do the first heart attack to herself)

After the first heart attack, had she maintained the obesity, with all "current" associated problems, and possibly new ones on top of that... then BAM, second heart attack... Is she dead? Could the body in the "compromised" state recover from the stress of a second attack? Or did her "improved capability" aid her surviving attack 2.

In regards to the second attack happening anyway.... Can cardiovascular disease be "undone", or is it like bending metal. Once metal is bent so far as to permanently deform it, it can not be undone. So, once you experience the first heart attack, you are ALWAYS at risk for a second?

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Old Yesterday, 02:58 PM ? #3

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Quote:

Glad she is fine.

A couple of thoughts....

Does she have a family history of cardiovascular disease? That is also a semi-rhetorical question. Just because she can answer that question as a "NO" to the best of her knowledge doesn't me that the absolute answer is NO. The history could have been there without people realizing it. If the answer is "yes"... genetics are funny like that, and they can't be beat.

Had she always maintained a "healthy weight" and not gotten very heavy, with Type 2 Diabetes in the first place.. would she have had the first heart attack to begin with? (i.e. did she do the first heart attack to herself)

After the first heart attack, had she maintained the obesity, with all "current" associated problems, and possibly new ones on top of that... then BAM, second heart attack... Is she dead? Could the body in the "compromised" state recover from the stress of a second attack? Or did her "improved capability" aid her surviving attack 2.

In regards to the second attack happening anyway.... Can cardiovascular disease be "undone", or is it like bending metal. Once metal is bent so far as to permanently deform it, it can not be undone. So, once you experience the first heart attack, you are ALWAYS at risk for a second?

Funny you should ask as she had a family history of both heart disease and diabetes, so you could have predicted both.

She was always overweight as an adult, but she perceived that her pronounced obesity happened fairly precipitously. And evidence is emerging that diabetes and obesity go hand-in-hand, as if they shared a common genetic marker.

In fact, she told me her doctor had her frustrated and hopelessly confused by simultaneously ordering her to lose weight and also warning her that, owing to her diabetes, it would be nearly impossible to lose weight. Maybe he was half-right ?

The badgering to lose weight seems increasingly odd in light of studies that show that obese diabetics seem to survive their diabetes and heart attacks more readily than thin diabetics and heart attack victims do. This is precisely the reason researchers coined the term 'Obesity Paradox' awhile back. In my mind, how much longer should obesity be characterized as a risk when, more and more it seems like obesity (save the upper ranges) appears to be a benefit ?

Where should my client go from here ? In a sense, she's not unlike me with my hypertension. Eating normally, being active, managing stress, etc., can hardly hurt. But in her case, since her mother died in her 50's and father in his 60's, I somehow doubt that she's going to wind up a female Methuselah.

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Old Yesterday, 06:23 PM ? #17

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Sure, but you get them in your food. Look, I don't tell people not to take supplements For one thing, that approach never seems to work. Telling someone not to take something seems to have the opposite effect.

But other than creatine, most supplements don't really do what they say they're supposed to do. Take whey protein, for instance. Yes, it does induce protein synthesis. No, there is no hard evidence that protein synthesis actually promotes muscle growth long-term.

Remember that Placebo Effect is a powerful phenomenon. My wife where's those stupid copper bracelets. She acknowledges that it's probably bullshit, but swears that she feels better when she wears them.

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Old Yesterday, 06:42 PM ? #18

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Quote:

Sure, but you get them in your food. Look, I don't tell people not to take supplements For one thing, that approach never seems to work. Telling someone not to take something seems to have the opposite effect.

But other than creatine, most supplements don't really do what they say they're supposed to do. Take whey protein, for instance. Yes, it does induce protein synthesis. No, there is no hard evidence that protein synthesis actually promotes muscle growth long-term.

Remember that Placebo Effect is a powerful phenomenon. My wife where's those stupid copper bracelets. She acknowledges that it's probably bullshit, but swears that she feels better when she wears them.

Those damn copper bracelets.

I do take in some creatine, but not that much and not the monohydrate crap. I do beaf protein and it works. I've worked out without aminos and I've worked out with them, and I can tell you that the size and strength difference is not something that a placebo affect can explain.

It's as real as the difference between a skinny dude that is lean but skinny, seemingly okay, versus a dude that's built and muscular.

I buy only the highest quality American made amino acids...... and they do work.

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